-, Neoh CY, Tan AW, Mohamed K, et al. The papulovesicular and pityriasis rosea . National Library of Medicine 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. The site is secure. JAAD Case Rep 2018; 4: 800801. Epub 2022 May 31. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. If you develop pityriasis rosea, you may experience the following in this order: Feel ill for 1 or 2 days. eCollection 2022. Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. [Epub ahead of print]. Under the treatment that was initiated a partial remission of the lesions after 7 days was observed. Recurrent and persistent pityriasis rosea: an atypical case presentation. 2020 Sep 25;155(6):273. doi: 10.1016/j.medcli.2020.05.024. 8600 Rockville Pike Epub 2020 Nov 20. The site is secure. 2022 Aug 11;9(8):43. doi: 10.3390/medicines9080043. Most of the rare, severe allergic reactions to these vaccines have occurred in people with a history of allergies. doi: 10.1002/ccr3.6096. Appointments 216.444.5725 Appointments & Locations Request an Appointment It could be pityriasis rosea here's how to treat it. J Eur Acad Dermatol Venereol. Disclaimer. Coronavirus disease 2019 and pityriasis rosea: A review of the immunological connection. Before Studies show that some skin conditions may appear with COVID-19, including pityriasis rosea. HHS Vulnerability Disclosure, Help Br J Dermatol 2020; 183: 431442. Sriphojanart T, Khunkhet S, Suchonwanit P. A retrospective comparative study of the efficacy and safety of two regimens of diphenylcyclopropenone in the treatment of recalcitrant alopecia areata. Authors Jordan E Buckley 1 , Laura N Landis 2 , Ronald P Rapini 1 Affiliations Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. An official website of the United States government. Epub 2021 May 10. Epub 2022 Jun 19. doi: 10.1111/jdv.12942, 13. Figure 2. -, Mahajan K, Relhan V, Relhan AK, et al. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Epub 2022 Jan 5. -, Broccolo F, Drago F, Careddu AM, et al. headache.2 Several cutaneous adverse events after anti-COVID-19 vaccination are described in the literature, such as delayed large local reaction, urticaria, morbilliform eruptions, herpes zoster, "COVID arm," pityriasis rosea.3,4,5 Here, we report a case of a patient who presented with herpes zoster ophthalmicus (HZO) after the third dose Cebeci Kahraman F, Sava Erdoan S, Akta ND, Albayrak H, Trkmen D, Borlu M, Arca DA, Demirba A, Akbayrak A, Polat Ekinci A, Gkek GE, elik HA, Taolar MK, An , Temiz SA, Hazinedar E, Ayhan E, Hzl P, Solak E, Kl A, Ylmaz E. J Cosmet Dermatol. doi: 10.1016/j.jaad.20.2103.092. 2021 Aug;35(8):e491-e493. Atzori L, Pinna AL, Ferreli C, Aste N. Pityriasis rosea-like adverse reaction: review of the literature and experience of an Italian drug-surveillance center. Human herpesvirus-6,7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Sprinkle bath water with an oatmeal-based bath product (Aveeno). The site is secure. Rybak-d'Obyrn J, Placek W, Owczarczyk-Saczonek A, Derkaczew M, Joniec E, Hofman R, Stompr M. Clin Cosmet Investig Dermatol. The .gov means its official. The appearance of pityriasis rosea following the first injection of the AstraZeneca vector vaccine suggests a causal connection. The exanthem was self-limited in both patients over a period of a month. 2022 May;11(2):222-225. doi: 10.7774/cevr.2022.11.2.222. Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination. However, a fungus causes ringworm. (Within two days, and still no.) Pityriasis rosea: An update on etiopathogenesis and management of difficult aspects. Clinical aspect of the lesions after 7 days of treatment. A more recent letter in the International Journal of Dermatology reported a "unique case of pityriasis rosea following administration of mRNA COVID-19 vaccine." Treatment may include various topical and oral drugs. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). HHS Vulnerability Disclosure, Help FOIA Disclaimer. Epub 2022 Jan 5. If you have pityriasis rosea, its unlikely that youll get it again. 9 , 10 These findings suggest that immuneinduced viral reactivation - rather than The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. This rash is thought to be caused by a virus. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291919/). Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. Before Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Please enable it to take advantage of the complete set of features! Epub 2022 Jun 26. 2022 by the American Academy of Dermatology, Inc. Pityriasis rosea-like Covid-arm Erythema multiforme Erythroderma Psoriasis Others Grover-like eruptions Herpes simplex reactivation: 24 1 17 4 2 2 1 1 20 15 9 5 2 1 1 1 3 3: 21.5 0.9 15 3.5 1.8 1.8 0.9 0.9 PMC Epub 2020 Jun 5. (2021) 35:e5468. Diagnoses: Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. Int J Infect Dis. eCollection 2022 Jul. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. Pityriasis lichenoides is a clonal T-cell disorder that may develop in response to foreign antigens (eg, infections or drugs) and may be associated with cutaneous T-cell lymphoma. Among 171 laboratory-confirmed COVID-19 patients with cutaneous manifestations from the registry, the most commonly reported were morbilliform rash (22 percent), pernio-like acral lesions (18 percent), urticaria (16 percent), macular erythema (13 percent), vesicular eruption (11 percent), papulosquamous eruption (9.9 percent), and retiform In addition to a corticosteroid cream, New York City-based dermatologist Macrene Alexiades recommends keeping showers short and lukewarm, as "water, sweat, and soap reportedly irritate and inflame the lesions. A woman. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. The herald patch is the telltale sign that your rash could be PR, but there are other common (though not universal) symptoms as well. See this image and copyright information in PMC. Lasers Med Sci. Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH The patient developed papulovesicular lesions in the crease lines of the trunk and extremities, four days after inoculation with a recombinant coronavirus vaccine (Covishield, India). Contact your healthcare provider as soon as you notice a rash. Dos Santos PG, Vieira HCVS, Wietholter V, Gallina JP, Andrade TR, Marinowic DR, Zanirati GG, da Costa JC. Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. J Eur Acad Dermatol Venereol 2016; 30: 544-545. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. Advertising on our site helps support our mission. World J Clin Cases. doi: 10.1016/j.jdcr.2018.04.002, 12. Disclaimer. However, if you experience any symptoms, therapy can provide relief. doi: 10.7759/cureus.22414. Get useful, helpful and relevant health + wellness information. (2016) 30:5445. . eCollection 2022. Federal government websites often end in .gov or .mil. Accessibility The https:// ensures that you are connecting to the Dermatol Ther. Various mild and benign cutaneous manifestations of the different forms of the COVID-19 vaccine have been documented. F. Drago, G. Ciccarese, A. Parodi It said blood spots under the skin might also be present, either as spots or dots or on larger areas. Bookshelf Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Clinical aspect of the lesions after 7days of treatment. See this image and copyright information in PMC. FOIA Unable to load your collection due to an error, Unable to load your delegates due to an error. To the best of our knowledge, only one case of ChAdOx1 nCoV-19 vaccine-induced PR-like eruption has been reported (2). 2023 Cond Nast. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. sharing sensitive information, make sure youre on a federal 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. Pityriasis rosea (pih-tuh-RY-uh-sis ROH-zee-uh) is a common skin condition that causes patches of your skin to develop raised, scaly rashes. Nevertheless, she did not present with fever or respiratory tract symptoms. In some cases, central hyperpigmentation was identified. However, several adverse effects of COVID-19 vaccination have been identified. -, Drago F, Ciccarese G, Parodi A. Pityriasis rosea and pityriasis rosealike eruptions: how to distinguish them? Women are 50% more likely to develop pityriasis rosea. Br J Dermatol. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. (A) Dermoscopic features: dotted and linear vessels forming a network on a yellowish background with some whitish peripheral scales (original magnification x20). Epub 2022 Jun 8. FOIA It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. Herzum A, Trave I, D'Agostino F, Burlando M, Cozzani E, Parodi A. Clin Exp Vaccine Res. Bookshelf Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. The patient presented to the Department of Dermatology for a 3 week duration of an extremely pruritic erythematous-squamous lesion, initially on the trunk and upper limbs, with extension to the lower limbs in the last week and the lesion respected the cephalic extremity, palms, and soles. government site. Ciccarese G, Parodi A, Drago F. SARS-CoV-2 as possible inducer of viral reactivations. Vaccination is one of the cornerstones in the efforts towards ending the coronavirus disease 2019 (COVID-19) pandemic. However, pityriasis rosea can look similar to other skin conditions, including: If theres any doubt, your healthcare provider may perform the following tests: In most cases, pityriasis rosea goes away without any treatment in six to eight weeks. eCollection 2022. Please enable it to take advantage of the complete set of features! Epub 2021 Aug 26. . J Formos Med Assoc. J Eur Acad Dermatol Venereol 2020;34:e4367. Epub 2021 Apr 26. (2006) 12:1. doi: 10.5070/D380D8301D, 11. J Eur Acad Dermatol Venereol 2016; 30: 544545. Accessibility It was found on younger COVID-19 patients suffering milder forms of the virus. J Am Acad Dermatol. government site. 2022 Mar 9;35(3):342-343. doi: 10.1080/08998280.2022.2044742. PMC Medicines (Basel). Pityriasis rosea usually resolves on its own without treatment in most cases, King says, but topical corticosteroids can be used for itchy control if necessary, which is what I used. . Lessons: The rash itself usually doesnt blister or bleed, but in many cases, the skin may peel. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. Clipboard, Search History, and several other advanced features are temporarily unavailable. Accessibility (c) Patient 2: Thin red to tan oval plaques with peripheral scale on the trunk and proximal thigh. Federal government websites often end in .gov or .mil. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Would you like email updates of new search results? Though pityriasis rosea is a common skin rash, it can still make you feel self-conscious, and it can be unpleasant if it itches. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. Clipboard, Search History, and several other advanced features are temporarily unavailable. J Eur Acad Dermatol Venereol. Authors B M Cyrenne 1 , F Al-Mohammedi 1 , J G DeKoven 1 , R Alhusayen 1 Affiliation 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Unauthorized use of these marks is strictly prohibited. Rationale: Pityriasis Rosea. retailers. (No.) In: Knoop KJ, Stack LB, Storrow AB, et al., eds. This site needs JavaScript to work properly. How can you tell that I have pityriasis rosea? "However, it's possible to develop the rash more than once," she says. Its important to pay attention to your skin. J Med Virol 2021; 93: 1850-1851. PS conceptualized the case report and revised the manuscript. Federal government websites often end in .gov or .mil. Some rare cases can take up to three months. Pityriasis rosea Gibert is an erythematous-papulosquamous dermatosis that frequently occurs in young adults. Refined carbohydrates, such as sugar, pastries and white bread. doi: 10.1111/dth.13878, 10. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. (b) haematoxylineosin, original magnification 20. Hum Vaccin Immunother. Unauthorized use of these marks is strictly prohibited. doi: 10.1111/dth.13650, 7. Br J Dermatol. Clinical manifestations and histopathologic findings of reported patients with pityriasis-rosea like eruptions following COVID-19 vaccination. Other plausible theories include molecular mimicry with viral epitopes and type IV delayed hypersensitivity reaction (12). doi: 10.1002/jmv.26549, 9. Int J Infect Dis. Do the medications have any side effects? The patients/participants provided their written informed consent to participate in this study. and transmitted securely. Last reviewed by a Cleveland Clinic medical professional on 06/17/2022. Parakeratosis with minimal acanthosis and spongiosis of the epidermis. Pityriasis rosea isnt a sexually transmitted disease or infection (STD or STI). Bin Rubaian NF, Almuhaidib SR, Aljarri SA, Alamri AS. 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. Epub 2022 May 3. Yes, There Is a Correct Order for Everything You Do in the Shower, Each Zodiac Sign's Unique Personality Traits, Swoopy 1960s Hair Was Everywhere at the SAG Awards, Christina Aguilera Opened Up About Getting Injections and Why She Doesn't Care If People Judge Her, "I think we all can rely on a little help. official website and that any information you provide is encrypted Would you like email updates of new search results? Human herpesvirus6, 7, and EpsteinBarr virus reactivation in pityriasis rosea during COVID19. Med. Get more info about other skin conditions: The Ultimate Guide to Skin Conditions for Black & Brown Folks, I Thought I Just Had Dry Skin, But It Was Actually Perioral Dermatitis, Everything You Should Know About Hidradenitis Suppurativa. The condition is more prevalent in spring and fall. Epub 2022 Jan 31. Pityriasis lichenoides has distinct acute and chronic forms, which are usually distinct . "And it has a particular [dermatomal] distribution because it's along a nerve," which also presents as fluid-filled blisters, rather than lesions. 2022 Jul 21;14(7):e27108. Drago F, Ciccarese G, Rebora A, Parodi A. The good news is many of those who develop pityriasis rosea never get it again, says New York City-based dermatologist Hadley King. We do not endorse non-Cleveland Clinic products or services. Dermatology. | Pityriasis Rosea, COVID-19 and . Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. Clipboard, Search History, and several other advanced features are temporarily unavailable. (a) Patient 1: Thin, Histopathological findings of pityriasis rosealike, Histopathological findings of pityriasis rosealike eruption in patient 1. J Med Virol 2021; 93: 18501851. official website and that any information you provide is encrypted Got an extremely itchy rash that came seemingly out of nowhere? Though there's no single-known cause, it may be brought on by a drug interaction, or the reactivation of herpes simplex virus 6 or 7. (2021) 60:11501. Suchonwanit P, Hector CE, Bin Saif GA, McMichael AJ. doi: 10.1016/j.jaad.2020.04.094, 8. Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements. National Library of Medicine Cutaneous manifestation has been reported in 0.2% of patients infected by COVID-19 in China, and 18 out of 88 patients from Italy. doi: 10.1111/dth.13730. Some people who have had cosmetic fillers used to remove . 2022 Dec;9:127. doi: 10.1016/j.jdin.2022.03.018. Dermatol Ther. -. Also, topical medication with dermatocorticosteroids and emollients was associated. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. Federal government websites often end in .gov or .mil. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. Few scattered dyskeratotic keratinocytes are seen in the lower epidermis. Marcantonio-Santa Cruz OY, Vidal-Navarro A, Pesqu D, Gimnez-Arnau AM, Pujol RM, Martin-Ezquerra G. J Eur Acad Dermatol Venereol. The patient had a positive RT-PCR result, and was confirmed with SARS-CoV-2 infection. Laboratory investigation results (i.e., complete blood count, blood chemistry, C-reactive protein level, erythrocyte sedimentation rate, serological test for syphilis, plasma polymerase chain reaction (PCR) for human herpesvirus (HHV)-6 and HHV-7, and reverse transcription-PCR for COVID-19) were unremarkable. I put on some hydrocortisone and went to sleep, then woke up with another mark on my side, a couple inches below my armpit. "Like a lot of things in dermatology, unfortunately, we're not always sure what causes these rashes," says Lam. Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of COVID19. Cazzato G, Ambrogio F, Pisani MC, Colagrande A, Arezzo F, Cascardi E, Dellino M, Macorano E, Trilli I, Parente P, Lettini T, Romita P, Marzullo A, Ingravallo G, Foti C. Vaccines (Basel). Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. Dermatol Reports. Front. Keywords: These findings were consistent with a diagnosis of PR-like eruption. Borgia F, Li Pomi F, Alessandrello C, Vaccaro M, Pioggia G, Gangemi S. J Dermatol. However, several adverse effects of COVID-19 vaccination have been identified. If you have pityriasis rosea, the rash with go away without treatment. You also wont have permanent scarring or other damage to your skin. In: Papadakis MA, McPhee SJ, Bernstein J., eds. An official website of the United States government. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). "Other treatments including phototherapy or oral medications can be considered for extensive or persistent cases, [and] some small case studies support the use of oral antivirals like acyclovir or oral anti-inflammatory antibiotics erythromycin," King explains. Ramot Y, Nanova K, Faitatziadou SM, Assab DA, Berkun Y, Zlotogorski A. J Dtsch Dermatol Ges. (2017) 9:7399. doi: 10.4081/dr.2017.7399, 17. Epub 2022 Jun 13. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. Before Epub 2021 Aug 7. 8 PDF Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases D. McMahon, E. Amerson, +11 authors E. Freeman Medicine Martn Enguix D, Salazar Nievas MDC, Martn Romero DT. Here, we report the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. Pityriasis rosea-like eruption revealing COVID-19. Marzano AV, Cassano N, Genovese G, Moltrasio C, Vena GA. Cutaneous manifestations in patients with COVID19: a preliminary review of an emerging issue. You may develop a raised, discolored, circular or oval-shaped patch that ranges from 1 to 6 centimeters (cm). It often presents with diffuse and confluent severely pruritic dusky-red erythematous lesions in the absence of herald patch (11). If you have pityriasis rosea, it can generally be well-managed without any treatment. -. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. These conditions lasted 8.6 days on average. MeSH Physical examination revealed that lesions were distributed along cleavage lines, similar to PR, without herald patch or prominent scales (Figure 1C). However, there isnt enough research to determine that stress may cause pityriasis rosea. While you don't need to treat the rash, some patients ask for treatment to take care of the following. Br J Dermatol. Br J Dermatol. The available COVID-19 vaccines entail different levels of risk for skin reactions. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. This tiny glimpse of her natural texture is thrilling. Before 2020 Jul;33(4):e13730. Before The site is secure. The .gov means its official. One case of pityriasis rosea is reported in a patient infected with COVID-19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). Similar to other viral outbreaks, people can experience flu-like symptoms like a fever, aches, or a runny nose when the herald patch shows up, Lam says, though I was lucky enough to skip that step. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Blood tests to check for causes of a rash that arent related to pityriasis rosea. National Library of Medicine Among the common cutaneous manifestations of COVID-19 (e.g., morbilliform eruptions, chilblains, and varicella-like vesicles), PR and PR-like eruptions have rarely been described (6, 7). One case of pityriasis rosea is reported in a patient infected with COVID19, and the most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy. Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. MeSH Some treatments can alleviate related symptoms, including itching. Abdullah L, Hasbani D, Kurban M, Abbas O. Pityriasis rosea after mRNA COVID-19 vaccination. They were found on hands and feet, showing up as red or purple spots caused by bleeding under the skin. Atypical pityriasis rosea associated with mRNA COVID19 vaccine E. Bostan, Adam Jarbou Published 29 September 2021 Medicine Journal of Medical Virology Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of Covid-19. Your symptoms dont improve after treatment. How quickly did it come on, and did my boyfriend also have it? KL and KP collated resources. The transformation will take your breath away. We present two cases of COVID-19 vaccine-induced pityriasis rosea. Cutis. Here, we describe a case of PR-like eruption following ChAdOx1 nCoV-19 (AZD1222) vaccination in a Thai patient with glioblastoma. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. doi: 10.1111/jdv.17342. 2021;184(6):11941195. Keywords: User Agreement and Privacy Policy and Cookie Statement and . Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. Authors Elina Khattab 1 , Eirini Christaki 2 , Constantinos Pitsios 1 Affiliations 1 Medical School, University of Cyprus, Nicosia, Cyprus. 8600 Rockville Pike Epub 2022 Feb 9. They indicate that eight types of rash could be signs of Covid-19, including red toes and fingers, chest eczema and pityriasis rosea (scroll down for the full list). Alamri A, Alghamdi Y, Alamri SJ, Althaqafi MK, AlQurashi W, Bader BA, Mohanna AT, Almahdi B. Cureus. Treatment was initiated with systemic corticosteroid therapy - hydrocortisone hemisuccinate 200 mg/day for 7 days, and loratadine 10 mg 2 times a day. An official website of the United States government. The cause of pityriasis rosea is not known, but it is commonly believed to be caused by a virus or bacteria. This site needs JavaScript to work properly. government site. Vaccinations have been identified to rarely cause several cutaneous reactions. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Epstein-Barr virus reactivation after COVID-19 vaccination in a young immunocompetent man: a case report. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. The authors of one 2014 case report of a 71-year-old man who suffered from pityriasis rosea one month after receiving an influenza vaccine concluded that "altered immunity" could result in reactivation of HHV-6 and/or HHV-7 which may have triggered an atypical presentation of PR. The https:// ensures that you are connecting to the These strains of the herpes virus arent related to the strains that cause cold sores or genital herpes. MeSH Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. 18. PMC doi: 10.1111/bjd.20143. -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. Europe PMC is an archive of life sciences journal literature. (2015) 2015:253154. doi: 10.1155/2015/253154, 14. Unable to load your collection due to an error, Unable to load your delegates due to an error. 2022 Sep-Oct;40(5):586-590. doi: 10.1016/j.clindermatol.2022.01.002. 2021 Jun 25;118(25):431. doi: 10.3238/arztebl.m2021.0257. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection Pityriasis rosea as a cutaneous manifestation of COVID-19 infection J Eur Acad Dermatol Venereol. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. (Unfortunately, I scratched my rash until it bled, so my hyperpigmentation may linger.). It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Parakeratosis with minimal acanthosis, MeSH Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, et al. A few days later, the cluster came: Ten little dots arranged themselves in a perfect alien-like crop circle on my upper back, and they itched so much that I scratched them raw. Policy. The https:// ensures that you are connecting to the doi: 10.1111/jdv.17301. Among patients who received COVID-19 vaccines, PR-like eruptions have been reported following the first (n = 1) or second dose (n = 2) of BNT162b2 mRNA-based vaccines (3, 4). Epub 2021 Apr 7. Some people develop a few large patches on their skin. 8600 Rockville Pike Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. J Eur Acad Dermatol Venereol 2020; 34: e436-e437.